Detalhe da pesquisa
1.
Mast cells link immune sensing to antigen-avoidance behaviour.
Nature
; 620(7974): 634-642, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37438525
2.
Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis.
Kidney Int
; 87(6): 1125-40, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25651362
3.
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury.
J Am Soc Nephrol
; 23(5): 868-83, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383695
4.
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis.
Sci Transl Med
; 15(698): eabn0736, 2023 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37256934
5.
Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease.
iScience
; 24(10): 103193, 2021 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34703992
6.
A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation.
Cell Physiol Biochem
; 26(1): 97-104, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20502009
7.
Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.
Kidney Int
; 76(8): 857-67, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19657322
8.
The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.
Br J Pharmacol
; 147(2): 164-74, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16299553
9.
Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells.
Biochim Biophys Acta
; 1636(2-3): 159-68, 2004 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15164763
10.
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
J Clin Invest
; 125(1): 141-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415439
11.
Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.
Br J Pharmacol
; 143(5): 581-9, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15466446
12.
Interleukin-1beta inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide.
Br J Pharmacol
; 138(3): 461-8, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12569071
13.
Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase.
Eur J Pharmacol
; 442(3): 195-203, 2002 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12065072
14.
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Sci Transl Med
; 4(121): 121ra18, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344686
15.
Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage.
Br J Pharmacol
; 162(2): 532-43, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20883472
16.
Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation.
J Lipid Res
; 48(9): 1985-96, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17592175
17.
Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
J Biol Chem
; 280(47): 39403-16, 2005 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16183640
18.
PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism.
Biochem Biophys Res Commun
; 338(4): 1818-24, 2005 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-16288986
19.
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses.
J Biol Chem
; 279(34): 35255-62, 2004 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15192102